MIR

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MIR is a computational method to infer relative activities miRNAs by integrating microarray expression data with miRNA target predictions.

[edit] Availability

  • research.ist.unomaha.edu

[edit] Installation

In a Windows box, do the following to install MIR:

1. Go to this site and select the Download link and download the file microRNA(whole package).zip file.  
2. Place the extracted directory files in C:\Program Files\MIR\.

[edit] How to run

1. Please read the readme.doc file inside the extracted folder on how to run the tool.
2. For testing the example data, rename the Example miRNA-gene binding affinity data --nomirna_genename.txt 
   file to knomiRNA_GeneName.txt and rename the ExampleMicroarrayData--mir_hela_transfection.txt to
   miR_Hela_Transfection.txt.
3. Run the run.bat file by right clicking it. This will run MIR on the above example input files. 
4. Otherwise, start a command prompt (DOS) and go to the directory containing all the input files and then iterating to 
   C:\Program Files\MIR\ and run the WinMIR.exe command. 
   Read the readme.doc file for understanding the input files and parameters to pass to WinMIR.exe.